Unlocking Insights
in CLL

CLL Dataset Insights

Our dataset* provides valuable insights into CLL, including but not limited to:

CLL Dataset Insights

Our dataset* provides valuable insights into CLL, including but not limited to:

+800

Estimated N CLL Patients

10.5%

Average 1 year mortality %

6.2

years

Mean FU period

48

visits

Average visits per patient

44.9%

% Patients BTKI* treatment

74.8

years

Average age at diagnosis

452

Endpoints

Request feasibility check

* Bruton Tyrosine Kinase Inhibitor

Note that the estimated patient counts provided (prior to inclusion/exclusion criteria) are specific to our Belgian dataset. Details on the representativeness and diversity of the Belgian dataset for global studies can be found above. The LynxCare datasets continue to expand, encompassing real-world data from hospitals across Europe. Complete the form on the right to gain further details and to discuss your study needs with one of our RWE experts.

Closing the Gap

The Value of Unstructured Data in the CLL Pathway

Structured vs. Unstructured

Structured data alone only provides part of the picture, missing key nuances.Combining structured data with rich EHR narrative datacan improve our understanding of CLL pathophysiology andoutcomes, as evidenced by our data which yielded a higher morbidity index of 34% compared to 28% with structured data alone.

RCT vs. RWE

In the era of small molecule inhibitor targeted therapies, the landscape of chronic lymphocytic leukemia (CLL) has undergone a breathtaking transformation. While randomized controlled trials(RCTs) remain the gold standard, they are often unable to keep pace with the clinical questions that arise during the use of novel agents.

Real-World Insights

Using our federated real-world dataset, we can analyze adverse events, OS, and treatment patterns in real time, providing invaluable insights into the patient pathway of CLL.

Unpacking The Data

The Sources Behind Our Insights

Clinical Addessments

  • Patient demographics
  • Vital signs
  • Claims data
  • Biomarkers
  • Medications
  • Tumor staging

Medical records

  • Active and inactive medical problems
  • Surgical interventions
  • Hospital procedures, visits & hospitalizations
  • In and out of hospital mortality

Treatment data

  • Drug regimens
  • Doses and durations of chemotherapy
  • Immuno-Modulary treatments

Molecular Data Points

  • Gene expression profiles
  • Molecular-level information

Unlock Research Questions

Our dataset offers life science companies unparalleled insights into the relationship between specific biomarkers, comorbidities, and treatment outcomes in CLL.

Research Question/
Endpoints

Demographics

Cancer type

Histology

Comorbidities

Lab results

Cancer treatment

Hospital visit &
admissions

Survival

Biomarkers
Genetic drivers

Outcomes

Adverse events

Complications

Titration / Dosing

Treatment dynamics

Incidence & Prevalence

Adherence

Efficacy

Indication split

Safety profile

How Pharma Can Leverage LynxCare's Dataset

Clinical Trial Design

Our granular and quality-controlled real-world dataset can help design clinical trials that better reflect real-world scenarios.

Synthetic Control Arm

Our dataset can be used to create synthetic control arms, which can be used to evaluate the effectiveness of new treatments.

Market Access

Our dataset can help pharma companies gain a better understanding of the market and generate granular value dossiers for HEOR.

Medical Affairs

Our dataset can help medical affairs teams better understand the clinical outcomes and real-world evidence associated with their products.

How Hospitals Can Benefit from a LynxCare Database

Improving Patient Care

Find more relevant medical information thanks to LynxCare's disease-specific NLP pipeline for a better patient and population understanding.

Research & Network Opportunities

Initiate or participate in national and international multi-center, multi-country RWE studies.

Benefit from network of KOLs.

Scientific Research

Initiate or participate in (pharma- or physician initiated) peer-reviewed (multi-center, multi-country) publications

Increased Clinical Trial Participation

More effective patients/cohort selection through clinical NLP, enrolling more patients in clinical trials

Improve your Data Quality

Receive feedback on the clinical data quality of your hospital’s database.

Benefit from data science training provided

World-Class Expertise.
The LynxCare Advantage

Representativity

We do our best to ensure representativity by including data from a mix of academic and non-academic centers. This captures the real-world patient and treatment pathway.

Data Experts

Our team of data experts has a combined 50+ years of experience in healthcare data analytics and quality control.

Clinical Experts

We partner with clinical experts in CLL and other specialties to ensure our data offers relevant and valuable insights for healthcare professionals.

Hospital Network & Data Access

The hospitals remain in control over their own data. Each RWE request is individually handled following data governance guidelines and timelines inour master service agreement to accelerate the delivery of insights.

Partnership with the best statistical firms

LynxCare partners with statistical firms who already have a working relationship with the life science company.

Differentiating factors from other NLP providers & established RWD vendors

Breadth and Depth

Our data asset contains over 800 estimated CLL patients and 452 endpoints measured throughout the patient pathway, offering exceptional granularity for analysis.

Data Quality and Freshness

Our strict data quality standards and regular updates ensure that our dataset is both reliable and up-to-date, providing the most valuable insights for our clients.

Disease-specific NLP

Our NLP is disease-specific. As a result, the data is far more complete compared to other broad NLP vendors.

OMOP-CDM Data Warehouse

Our dataset is stored in the widely-used OMOP-CDM format, enabling our clients to easily integrate our data with other healthcare or research IT solutions.

Fast Data Access

We run projects on databases already built and manage your expectations upfront with a feasibility check for your study protocol.

Building Trust
Quality Control and Data Freshness

Patient Insights
More Than Numbers

The Future of CLL Treatment

How LynxCare Can Help

Personalized Medicine

With our comprehensive dataset and world-class expertise, LynxCare is well-positioned to help clinicians tailor treatments to specific patient needs, opening up the possibility of personalized medicine for CLL. Our data asset provides valuable insights into individual pathways of CLL patients, enabling clinicians to make more informed treatment decisions.

Improved Outcomes

Our data asset aims to ultimately improve patient outcomes by providing insights into the clinical pathway of CLL patients. By analysing real-world patient data, our dataset offers a unique perspective on the effectiveness and safety of different treatments. This information can help clinicians make more informed treatment decisions, leading to better outcomes for patients.

Continued Innovation

LynxCare is committed to driving innovation in CLL treatment and management. With our world-class expertise in data analysis and interpretation, we aim to continue to provide valuable insights and solutions to healthcare providers and researchers. Our comprehensive dataset offers a wealth of information for life science companies and other stakeholders interested in advancing CLL therapy.

Request feasibility assessment

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